Antibiotics Susceptibility Profile of <i>Staphylococcus aureus</i> Clinical Isolates Collected in Hospitals in the City of Douala (Cameroon)

Introduction: Staphylococcus aureus is one of the most important agents involved in community and hospital-acquired infections. Due to multi-drug resistance strains antibiotics, treatment eradicate it becoming more difficult poses a global public health problem. Methodology: This was cross-sectional study conducted from March August 2020 hospitals city Douala, including all S. isolates diagnostic samples. Strain identification antibiotic susceptibility testing were performed using Vitek2 CompactTM (BioMerieux). Results: During period, 136 non-repetitive identified with high frequency methicillin-resistant 78.7%. The majority originated Douala General Hospital (66.9%) frequently isolated blood culture samples (55.1%). biochemical characteristics showed that had between 87% 99% homology reference strain. active antibiotics Quinupristin/Dalfopristin (94.2%), Linezolid (87.8%) Vancomycin (84.2%). Methicillin associated decreased other such as Gentamycin (44.9%), Erythromycin (38.2%), Tetracycline (38.3%), Trimethoprim (21.4%), Ciprofloxacin (19.1%) Levofloxacin (24.0%). Inducible MLSb constitutive phenotypes 26.7% 22.8% respectively. Conclusion: sensitivity differs family another, remains good for molecules are not available our context. Methicillin-Resistant shows continuous progression multi-resistant their usual becomes alarming.